21679-14-1 Fludarabine Direct Factory Price

Product Details
Customization: Available
CAS No.: 21679-14-1
Formula: C10h12fn5o4
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Number of Employees
80
Year of Establishment
2009-01-21
  • 21679-14-1 Fludarabine Direct Factory Price
  • 21679-14-1 Fludarabine Direct Factory Price
  • 21679-14-1 Fludarabine Direct Factory Price
  • 21679-14-1 Fludarabine Direct Factory Price
  • 21679-14-1 Fludarabine Direct Factory Price
  • 21679-14-1 Fludarabine Direct Factory Price
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  • Overview
  • Product Description
  • Packaging & Shipping
  • Company Profile
Overview

Basic Info.

Model NO.
21679-14-1
EINECS
244-525-5
Classification
Biochemical Reagents
Specific Usage
For Biological Purpose
Content
Standard
Usage
Diagnostic Reagents
Application
Scientific Research, Health
Property
Biochemical Reagent
CAS
21679-14-1
Color
White
MW
285.23
Form
Powder
Mf
C10h12fn5o4
Transport Package
25kg/Package
Specification
1KG
Trademark
ECHEMI
Origin
China

Product Description

 

Product Description

 
Melting point  265-268°C
alpha  D25 +17 ±2.5° (c = 0.1 in ethanol)
Boiling point  747.3±70.0 °C(Predicted)
density  2.17±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMF: 20 mg/mL, clear, faintly yellow
form  Powder
pka 13.05±0.70(Predicted)
color  White to Pale Yellow
Water Solubility  Soluble in DMF, DMSO, methanol or ethanol. Sparingly soluble in water
Merck  13,4152
BRN  1225932
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI InChI=1/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/s3
InChIKey HBUBKKRHXORPQB-VOSPVXAENA-N
SMILES C12N=C(N=C(N)C=1N=CN2[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1)F |&1:10,11,13,15,r|
CAS DataBase Reference 21679-14-1(CAS DataBase Reference)

Fludarabine (21679-14-1) is a synthetic adenosine analog that inhibits DNA biosynthesis and is a clinically useful antineoplastic agent.1 In cells fludarabine accumulates as its 5'-triphosphate (F-ara-ATP) for which the rate-limiting step in formation is the conversion of fludarabine to its monophosphate.2 F-ara-ATP has multiple mechanisms of action including inhibition of ribonucleotide reductase, DNA polymerase, ligase and primase.2 A frequently used agent in myeloablative conditioning regimens for allogeneic hematopoietic cell transplantation.3 Immunosuppressive effects are mediated via inhibition of TNFa-stimulated production of IL-2 and IFN-g through inactivation of NFkB.4 Antagonist at adenosine A1 receptors.5

 

Packaging & Shipping

 

Packing : 200kg/drum

 

Delivery:  

  1. In stock products are normally shipping within 3 working days. 

  2. For rush delivery, please contact our sales team for particular arrangement.

Shipping:

  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.

  2. Shipping details & shipping documents will be provided and sent by email.

  3. We keep tracking the shippment until clients well received.

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently

Company Profile

21679-14-1 Fludarabine Direct Factory Price
21679-14-1 Fludarabine Direct Factory Price21679-14-1 Fludarabine Direct Factory Price

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