21679-14-1 Fludarabine Direct Factory Price

• Customization: Available
• CAS No.: 21679-14-1
• Formula: C10h12fn5o4
• Model NO.: 21679-14-1
• Classification: Biochemical Reagents
• Specific Usage: For Biological Purpose
• Content: Standard
• Usage: Diagnostic Reagents
• Application: Scientific Research, Health
• Property: Biochemical Reagent
• CAS: 21679-14-1
• Color: White
• MW: 285.23
• Form: Powder
• Mf: C10h12fn5o4
• Transport Package: 25kg/Package
• Specification: 1KG
• Trademark: ECHEMI
• Origin: China

Product Description

 

Product Description

 

Melting point	265-268°C
alpha	D25 +17 ±2.5° (c = 0.1 in ethanol)
Boiling point	747.3±70.0 °C(Predicted)
density	2.17±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMF: 20 mg/mL, clear, faintly yellow
form	Powder
pka	13.05±0.70(Predicted)
color	White to Pale Yellow
Water Solubility	Soluble in DMF, DMSO, methanol or ethanol. Sparingly soluble in water
Merck	13,4152
BRN	1225932
Stability:	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI	InChI=1/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/s3
InChIKey	HBUBKKRHXORPQB-VOSPVXAENA-N
SMILES	C12N=C(N=C(N)C=1N=CN2[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1)F |&1:10,11,13,15,r|
CAS DataBase Reference	21679-14-1(CAS DataBase Reference)

Fludarabine (21679-14-1) is a synthetic adenosine analog that inhibits DNA biosynthesis and is a clinically useful antineoplastic agent.1 In cells fludarabine accumulates as its 5'-triphosphate (F-ara-ATP) for which the rate-limiting step in formation is the conversion of fludarabine to its monophosphate.2 F-ara-ATP has multiple mechanisms of action including inhibition of ribonucleotide reductase, DNA polymerase, ligase and primase.2 A frequently used agent in myeloablative conditioning regimens for allogeneic hematopoietic cell transplantation.3 Immunosuppressive effects are mediated via inhibition of TNFa-stimulated production of IL-2 and IFN-g through inactivation of NFkB.4 Antagonist at adenosine A1 receptors.5

 

Packaging & Shipping

 

Packing : 200kg/drum

 

Delivery:  

1. In stock products are normally shipping within 3 working days. 

2. For rush delivery, please contact our sales team for particular arrangement.

Shipping:

1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.

2. Shipping details & shipping documents will be provided and sent by email.

3. We keep tracking the shippment until clients well received.

4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently

Company Profile