366789-02-8 Rivaroxaban Direct Manufacturer Supply

• Customization: Available
• CAS No.: 366789-02-8
• Formula: C19h18cln3o5s
• Model NO.: 366789-02-8
• Classification: Biochemical Reagents
• Specific Usage: For Biological Purpose
• Content: Standard
• Usage: Diagnostic Reagents
• Application: Scientific Research, Health
• Property: Biochemical Reagent
• CAS: 366789-02-8
• Color: White
• MW: 435.88
• Form: Powder
• Mf: C19h18cln3o5s
• Transport Package: 25kg/Package
• Specification: 1KG
• Trademark: ECHEMI
• Origin: China

Product Description

 

Product Description

 

Melting point	228-229°C
Boiling point	732.6±60.0 °C(Predicted)
density	1.460±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	insoluble in H2O; insoluble in EtOH; ≥13.9 mg/mL in DMSO with gentle warming
form	solid
pka	13.36±0.46(Predicted)
color	White to off-white
InChI	InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
InChIKey	KGFYHTZWPPHNLQ-AWEZNQCLSA-N
SMILES	C1(C(NC[C@@H]2OC(=O)N(C3=CC=C(N4CCOCC4=O)C=C3)C2)=O)SC(Cl)=CC=1

Rivaroxaban(366789-02-8) is an antithrombotic drug and was developed in a collaboration between the German Bayer Pharmaceuticals and American Johnson company. It is different from the traditional antithrombotic drug heparin in that Rivaroxaban does not need the participation of antithrombin III and can directly antagonize free and bound Xa factors. Heparin requires the effects of antithrombin III, and has no effect on Xa factors in the prothrombin complex. Rivaroxaban is the first oral direct Xa factor inhibitor in the whole world, and it can selectively and competitively inhibit free and bound Da factors as well as prothrombin activity. It uses a dose-dependent method to extend the partial thromboplastin time (PTT) and activated partial thromboplastin time (aPTT) to extend clotting time and lower thrombin genesis. Rivaroxaban has the characteristics of high bioavailability, wide range of target diseases, stable dose-effect relationship, easy oral intake, and low bleeding risk.
Rivaroxaban can also prevent and treat venous thrombosis. It is mainly used clinically to prevent deep venous thrombosis (DVT) and pulmonary embolism (PE) in adult patients following hip and knee replacement surgery. It is also used to prevent patients with nonvalvular atrial fibrillation from cerebral apoplexy and noncentral nervous system embolism, and it can lower the recurrence risk of coronary syndromes.
 

 

Packaging & Shipping

 

Packing : 200kg/drum

 

Delivery:  

1. In stock products are normally shipping within 3 working days. 

2. For rush delivery, please contact our sales team for particular arrangement.

Shipping:

1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.

2. Shipping details & shipping documents will be provided and sent by email.

3. We keep tracking the shippment until clients well received.

4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently

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